Found 2 Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM50577302'
Affinity DataIC50: 32nMAssay Description:Inhibition of DNA-PK (unknown origin) using biotin-PEG2-TWSLPLSQDSASE-amide as substrate incubated for 60 mins in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of DNA-PK in human HT-144 cells assessed as reduction in gammaH2AX phosphorylation incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair