Found 34 of kd for monomerid = 25761 TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 0.240nMAssay Description:Antagonist activity at human beta-2 adrenergic receptor expressed in salbutamol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluorescence co...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 0.603nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-2 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 0.830nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
Affinity DataKd: 1.26nMAssay Description:Ability to block Beta-2 adrenergic receptor in guinea pig trachea preparationMore data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:In vitro beta-1 adrenergic receptor activity was determined via inhibition of the positive chronotropic actions of isoproterenol in isolated guinea p...More data for this Ligand-Target Pair
Affinity DataKd: 1.78nMAssay Description:Compound was evaluated for competitive antagonism of beta-2 adrenergic receptor in rat uterus measured as pA2 (-log KB)More data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Antagonist activity at human beta-1 adrenergic receptor site 1 expressed in cimeterol-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluoresce...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Ability to block Beta-1 adrenergic receptor in guinea pig right atria preparationMore data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Beta-1 adrenergic receptor blocking activity in atria of guinea pig.More data for this Ligand-Target Pair
Affinity DataKd: 2.40nMAssay Description:Antagonism of the isoprenaline-induced positive chronotropic effect on the atria of guinea pigMore data for this Ligand-Target Pair
Affinity DataKd: 3.02nMAssay Description:In vitro beta-2 adrenergic receptor activity was determined by measuring inhibition of the isoproterenol induced relaxation in isolated guinea pig tr...More data for this Ligand-Target Pair
Affinity DataKd: 3.10nMAssay Description:Compound was evaluated for competitive antagonism of beta-1 adrenergic receptor in guinea pig atria measured as pA2 (-log KB)More data for this Ligand-Target Pair
Affinity DataKd: 3.39nMAssay Description:The apparent pA2 value was measured for beta-2 adrenergic blocking activity on the trachea of guinea pigMore data for this Ligand-Target Pair
Affinity DataKd: 3.39nMAssay Description:Beta-2 adrenergic receptor blocking activity in trachea of guinea pig.More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-1 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 6.90nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 7.90nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 8.70nMAssay Description:Antagonist activity of compound against Beta-1 adrenergic receptor in isolated guinea pig left atriaMore data for this Ligand-Target Pair
Affinity DataKd: 43.6nMAssay Description:Antagonist activity of compound against Beta-2 adrenergic receptor in isolated guinea pig tracheaMore data for this Ligand-Target Pair
Affinity DataKd: 117nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Displacement of [3H]DHA from inactive/G protein-uncoupled human beta2-AR expressed in CHO cell membranes assessed as intrinsic Kd by liquid scintilla...More data for this Ligand-Target Pair
Affinity DataKd: 162nMAssay Description:Antagonist activity at human beta-3 adrenergic receptor expressed in fenoterol-stimulated CHOK1 cells assessed as CRE-SPAP level by fluorescence corr...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Antagonist activity at human beta-1 adrenergic receptor site 1 expressed in CGP 12177-stimulated CHO-K1 cells assessed as CRE-SPAP level by fluoresce...More data for this Ligand-Target Pair
Affinity DataKd: 214nMAssay Description:Displacement of [3H]-CGP 12177 from human beta-3 adrenergic receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 500nMAssay Description:Binding affinity to TLX LBD expressed in His6-tagged Escherichia coli Rosetta assessed as binding constant measured after 300 sec at 200 mM by isothe...More data for this Ligand-Target Pair
Affinity DataKd: 3.55E+5nMAssay Description:Binding affinity to 50 uM human serum albumin at 10 uM by PAMPA methodMore data for this Ligand-Target Pair
Affinity DataKd: 4.37E+5nMAssay Description:Binding affinity to human serum albumin by PAMPA methodMore data for this Ligand-Target Pair
Affinity DataKd: 4.37E+5nMAssay Description:Binding affinity to 100 uM human serum albumin at 50 uM by PAMPA methodMore data for this Ligand-Target Pair
Affinity DataKd: 6.03E+5nMAssay Description:Binding affinity to 300 uM human serum albumin at 10 uM by PAMPA methodMore data for this Ligand-Target Pair
Affinity DataKd: 6.31E+5nMAssay Description:Binding affinity to 600 uM human serum albumin at 10 uM by PAMPA methodMore data for this Ligand-Target Pair
Affinity DataKd: 6.61E+5nMAssay Description:Binding affinity to 100 uM human serum albumin at 10 uM by PAMPA methodMore data for this Ligand-Target Pair
