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Found 3 Enz. Inhib. hit(s) with Target = '1,4-dihydroxy-2-naphthoyl-CoA synthase' and Ligand = 'BDBM50329085'
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  1.85E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as inhibition of enzyme-substrate com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataKi:  2.25E+4nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50329085((Z)-methyl 2-(6-chloro-2-oxo-2H-benzo[b][1,4]oxazi...)
Affinity DataIC50:  4.63E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed