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Found 3 Enz. Inhib. hit(s) with Target = '1,4-dihydroxy-2-naphthoyl-CoA synthase' and Ligand = 'BDBM50382337'
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
TBA

Curated by ChEMBL
LigandPNGBDBM50382337(CHEMBL2024335)
Affinity DataKi:  350nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
TBA

Curated by ChEMBL
LigandPNGBDBM50382337(CHEMBL2024335)
Affinity DataKi:  1.63E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,4-dihydroxy-2-naphthoyl-CoA synthase(Mycobacterium tuberculosis)
TBA

Curated by ChEMBL
LigandPNGBDBM50382337(CHEMBL2024335)
Affinity DataIC50:  468nMAssay Description:Inhibition of Mycobacterium tuberculosis MenB expressed in Escherichia coli BL21 (DE3) assessed as formation of DHNA-CoA from OSB-CoA by enzyme coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed