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Found 3 Enz. Inhib. hit(s) with Target = '1-deoxy-D-xylulose 5-phosphate reductoisomerase' and Ligand = 'BDBM50044976'
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataKi:  7.70E+3nMAssay Description:Uncompetitive inhibition of His-tagged Escherichia coli DXR at 1 to 8 uM pre-incubated for 2 mins before reaction initiation in presence of 160 uM NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed