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Found 6 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50193785'
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193785((3r,9r)-9-(4-((5-cyanopyridin-2-yloxy)methyl)-3,3-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed