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Found 4 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50252367'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252367(1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252367(1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  11nMAssay Description:Inhibition of C57BL/6 mouse 11betaHSD1 in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252367(1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat 11betaHSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50252367(1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed