Found 4 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50014695'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by cholesterol synthesis inhibition screen (CSI) in ratsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Compound was evaluated for binding affinity towards sigma opioid receptor using [3H](+)-3-PPP in guinea pig ileumMore data for this Ligand-Target Pair