Found 9 Enz. Inhib. hit(s) with Target = '3-oxo-5-alpha-steroid 4-dehydrogenase 1' and Ligand = 'BDBM50043604'
Affinity DataKi: 410nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Apparent inhibition constant towards human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rattus norvegicus)
UniversitäT Des Saarlandes
Curated by ChEMBL
UniversitäT Des Saarlandes
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against rat Steroid 5-alpha-reductase type I using 18213 3H testosterone 210 nM as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of type 1 steroid-5-alpha-reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human Steroid 5-alpha-reductase type IMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration of the compound against human Steroid 5-alpha-reductase type I in DU 145 cell culture using 3H androstenedione 5 nM as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant Steroid 5-alpha-reductase type I was evaluated as binding affinity of the compoundMore data for this Ligand-Target Pair