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Found 3 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM117036'
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM117036(US8664236, A16 | US9238651, A16)
Affinity DataIC50:  2.60nMpH: 8.0 T: 2°CAssay Description:The cellular assay for the determination of the PDK1 kinase activity is carried out as a Luminex assay in the 96-well format. PC3 cells are sown at...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM117036(US8664236, A16 | US9238651, A16)
Affinity DataIC50:  4.70nMAssay Description:The compound inhibits the target protein in the enzymatic PDK1 inhibition assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM117036(US8664236, A16 | US9238651, A16)
Affinity DataIC50:  4.70nMT: 2°CAssay Description:The experimental batches are carried out in a flashplate system with 384 wells/microtitration plate.In each case, the PDK1 sample His6-PDK1(Δ1-...More data for this Ligand-Target Pair
In DepthDetails US Patent