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Found 3 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM50321382'
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataEC50:  1.33E+5nMAssay Description:Competitive binding affinity to GST-PDK1 (unknown origin) preincubated for 1 to 10 mins by surface plasmon resonance in presence of biotin-PIFtideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataEC50:  1.33E+5nMAssay Description:Displacement of PIFtide from His-tagged PDK1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to PDK1 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed