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Found 4 Enz. Inhib. hit(s) with Target = '4,4'-diapophytoene synthase' and Ligand = 'BDBM50049236'
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 histidine-tagged full length CrtM expressed in Escherichia coli BL21(DE3) cells assessed as decrease i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataIC50:  83nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 full length His-tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells assesse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CrtM in Staphylococcus aureus assessed as reduction in staphyloxanthin levels after 72 hrs by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50049236((+/-)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed