Found 4 Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50088804'
Target4-hydroxyphenylpyruvate dioxygenase(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat liver cytosol HPPD using HPP as substrate assessed as reduction in O2 consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of Wistar rat liver HPPD using 4-Hydroxyphenylpyruvate as substrate assessed as reduction in oxygen consumption preincubated for 3 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of 4-hydroxyphenylpyruvate dioxygenase of purified pig liver by enol-borate methodMore data for this Ligand-Target Pair