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Found 4 Enz. Inhib. hit(s) with Target = '5'-nucleotidase' and Ligand = 'BDBM50561206'
Target5'-nucleotidase(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50561206(CHEMBL4764985)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins b...More data for this Ligand-Target Pair
Target5'-nucleotidase(Mus musculus)
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50561206(CHEMBL4764985)
Affinity DataEC50:  14nMAssay Description:Inhibition of CD73 in mouse EMT6 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and meas...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50561206(CHEMBL4764985)
Affinity DataEC50:  0.790nMAssay Description:Inhibition of CD73 in human NCI-H1568 cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and...More data for this Ligand-Target Pair
Target5'-nucleotidase(Homo sapiens (Human))
Oric Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50561206(CHEMBL4764985)
Affinity DataEC50:  0.220nMAssay Description:Inhibition of CD73 in human CD8+ T-cells assessed as reduction in AMP-induced ADO expression preincubated for 15 mins followed by AMP addition and me...More data for this Ligand-Target Pair