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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50454165'
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50454165(CHEMBL4218720)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta scintillation counting analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50454165(CHEMBL4218720)
Affinity DataEC50:  40nMAssay Description:Agonist activity at 5-HT1A receptor in Sprague-Dawley rat hippocampal membranes after 90 mins by microbeta scintillation counting based [35S]GTPgamma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM50454165(CHEMBL4218720)
Affinity DataEC50:  126nMAssay Description:Antagonist activity at 5-HT1A receptor in Sprague-Dawley rat hippocampal membranes assessed as inhibition of 8-OH-DPAT-induced receptor activation af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed