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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50596945'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.575nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596945(CHEMBL5207529)
Affinity DataEC50:  0.580nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed