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Report error Found 28 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM21398'
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity towards 5-HT2C receptor from rat using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]mesulergine binding to 5-hydroxytryptamine 2C receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Affinity towards 5-hydroxytryptamine 2C receptor in membranes from pig choroid plexus using [3H]N-methyl-mesulergineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  35.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.51E+3nMAssay Description:In vitro ability to displace [3H]mesulergine binding from 5-hydroxytryptamine 2C receptor from bovine choroid plexus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.09E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.95E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.95E+3nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H]Mesulergine from rat 5-HT2C receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Pig)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity towards human serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  7.24E+3nMAssay Description:Binding affinity towards serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [3H]mesulergine human cloned serotonin 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [3H]mesulergine from human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  7.24E+3nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Pig)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Pig)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed