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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50081701'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Lophora

US Patent
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataKi:  140nMAssay Description:The binding affinities shown in table 5 of psilocin and compound 8 at various monoaminergic receptors were determined in radioligand competition bind...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Lophora

US Patent
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataIC50:  7.80nMAssay Description:Modulation of human 5HT2C expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Lophora

US Patent
LigandPNGBDBM50081701(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Affinity DataEC50:  30nMAssay Description:Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...More data for this Ligand-Target Pair