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Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50388686'
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataIC50:  483nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataEC50:  100nMAssay Description:Induction of 5-HT4 receptor-mediated contraction in guinea pig longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataEC50:  102nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed