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Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50388687'
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataKi:  12.6nMAssay Description:Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataKi:  19.9nMAssay Description:Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataEC50:  0.794nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50388687(CHEMBL538635)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as acumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed