Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM328379'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328379(6-chloro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328379(6-chloro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  0.210nMAssay Description:The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hec Pharm Group

Curated by ChEMBL
LigandPNGBDBM328379(6-chloro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Affinity DataIC50:  3.60nMAssay Description:Antagonist activity at recombinant human 5HT6R expressed in CHO cells assessed as inhibition of 5HT-stimulated cAMP accumulation incubated for 4 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed