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Found 2 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50291266'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50291266(CHEMBL4169236)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Palack£

Curated by ChEMBL
LigandPNGBDBM50291266(CHEMBL4169236)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at 5HT6R (unknown origin) transfected in NG108-15 cells co-transfected with CAMYEL assessed as reduction in cAMP levels after 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed