Report error Found 61 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM10755'
Affinity DataEC50: 5.70nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 cells by LANCE TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...More data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at human 5-HT7 receptor expressed in CHO-K1 cells assessed as increase in serotonin-induced cAMP level after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.40nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 cells by LANCE TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as increase in cAMP levels by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemil...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70nMAssay Description:Agonist activity at human 5-HT7A receptor expressed in HEK cell membranes incubated for 20 mins by cAMP functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 9.30nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
Affinity DataEC50: 9.33nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
Affinity DataEC50: 112nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.55nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.603nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]5-CT from human recombinant 5-HT7A receptor expressed in HEK cells by radioligand completion assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-5-HT from human 5-HT7 receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-5-HT from human 5-HT7 receptor expressed in CHOK1 cell membranes after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 7 human receptorsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity of compound towards rodent 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
