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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50253208'
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from rat cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-SB-26997 from human 5-HT7A receptor expressed in HEK293 cell membranes after 60 mins by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(GUINEA PIG)
Università

Curated by ChEMBL
LigandPNGBDBM50253208(CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...)
Affinity DataEC50:  4.50E+6nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed