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Found 7 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50458554'
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataKi:  70nMAssay Description:Human gene recombinant 5-HT7 receptor expressed in Chinese hamster ovary (CHO) cells was used. [3H]LSD 1 nM, the 5-HT7 receptor membrane (15 μg/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataKi:  71nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataIC50:  3.97E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataIC50:  3.98E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataEC50:  113nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458554(CHEMBL4218801)
Affinity DataEC50:  112nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed