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Found 2 Enz. Inhib. hit(s) with Target = '5-lipoxygenase' and Ligand = 'BDBM50038649'
Target5-lipoxygenase(Bos taurus)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50:  180nMAssay Description:Inhibition of 5-lipoxygenase in bovine PMNL cell assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-lipoxygenase(Bos taurus)
Merckle

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50:  760nMAssay Description:Inhibition of bovine 5-LOX assessed as inhibition of calcium ionophore A23187-induced leukotrine B4 formation by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed