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Found 3 Enz. Inhib. hit(s) with Target = '6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3' and Ligand = 'BDBM200906'
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50:  30nMAssay Description:Method A: The kinase activity of the bi-functional enzyme is readily quantified based on the production of F-2,6-P2 as described by Van Schaftingen e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50:  30nMAssay Description:Inhibition of PFKFB3 (unknown origin) by ADP-Glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM200906(US9233946, 5)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of PFKFB3 in human PANC-1 cells assessed as reduction in Fructose-2,6-Bisphosphate productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed