Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = '60 kDa heat shock protein, mitochondrial' and Ligand = 'BDBM50495811'
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as inhibition of denatured pig heart MDH refolding by meas...More data for this Ligand-Target Pair
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50495811(CHEMBL3115919)
Show SMILES Cn1c2ccccc2c(O)c(C(=O)Nc2ccncc2)c1=O
Show InChI InChI=1S/C16H13N3O3/c1-19-12-5-3-2-4-11(12)14(20)13(16(19)22)15(21)18-10-6-8-17-9-7-10/h2-9,20H,1H3,(H,17,18,21)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as reduction in denatured pig heart MDH ATPase activity by...More data for this Ligand-Target Pair