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Found 2 Enz. Inhib. hit(s) with Target = 'ADAMTS5' and Ligand = 'BDBM379676'
TargetADAMTS5(Rattus norvegicus (Rat))
Galapagos

US Patent
LigandPNGBDBM379676(US9926281, Compound 200 | US9926281, Compound 219)
Affinity DataIC50:  29nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetADAMTS5(Rattus norvegicus (Rat))
Galapagos

US Patent
LigandPNGBDBM379676(US9926281, Compound 200 | US9926281, Compound 219)
Affinity DataIC50:  135nMAssay Description:ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent