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Found 1 Enz. Inhib. hit(s) with Target = 'ADAMTS5' and Ligand = 'BDBM471764'
TargetADAMTS5(Rattus norvegicus (Rat))
Galapagos

US Patent
LigandPNGBDBM471764((5S)-5- cyclopropyl- 5-[(2S)-3-[4-(3- fluoro-5-met...)
Affinity DataIC50:  12.5nMAssay Description:TABLE VII: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent