Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human wild type ALK using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ALK L1196M (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK G1202R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ALK (unknown origin) incubated for 120 mins in presence of 33P-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair
Affinity DataKd: 5.70nMAssay Description:Kinase binding assays were performed at DiscoveRx using the general KINOMEscan Kd Protocol (Fabian, M. A. et al., “A small molecule-kinase interactio...More data for this Ligand-Target Pair