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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11' and Ligand = 'BDBM50190500'
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50190500(6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...)
Affinity DataIC50:  81nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50190500(6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...)
Affinity DataIC50:  3.60E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50190500(6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...)
Affinity DataEC50:  180nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed