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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-dependent Clp protease proteolytic subunit' and Ligand = 'BDBM50527098'
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50527098(CHEMBL4446834)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) pre-incubated for 10 mins be...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50527098(CHEMBL4446834)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of ClpP in methicillin-resistant Staphylococcus aureus ATCC 33591 assessed as reduction in bacteria-induced hemolysis of sheep erythrocyte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetATP-dependent Clp protease proteolytic subunit(Staphylococcus aureus (strain NCTC 8325))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50527098(CHEMBL4446834)
Affinity DataEC50:  1.27E+3nMAssay Description:Binding affinity to N-terminal His6-sumo-tagged full length Staphylococcus aureus ClpP expressed in Escherichia coli BL2 (DE3) assessed as shifting o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB