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Found 4 Enz. Inhib. hit(s) with Target = 'ATP-dependent molecular chaperone HSP82' and Ligand = 'BDBM68264'
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68264(Microlactone, 15i)
Affinity DataIC50:  160nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68264(Microlactone, 15i)
Affinity DataIC50:  220nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68264(Microlactone, 15i)
Affinity DataIC50:  4.30E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University of Nottingham

LigandPNGBDBM68264(Microlactone, 15i)
Affinity DataIC50:  4.90E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed