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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50353279'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353279(CHEMBL1830683 | CHEMBL259582)
Affinity DataEC50:  6.35E+3nMAssay Description:Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353279(CHEMBL1830683 | CHEMBL259582)
Affinity DataEC50:  6.35E+3nMAssay Description:Inhibition of human Pgp mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50353279(CHEMBL1830683 | CHEMBL259582)
Affinity DataEC50:  6.35E+3nMAssay Description:Activity at MDR1 (unknown origin) expressed in MDCK cells assessed as interference with calcein-AM efflux incubated for 30 mins prior to calcein-Am a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed