Found 3 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50353279'
Affinity DataEC50: 6.35E+3nMAssay Description:Inhibition of MDR1 (unknown origin) over-expressed in MDCK cells assessed as calcein accumulation incubated for 30 mins prior to Calcein-AM addition ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.35E+3nMAssay Description:Inhibition of human Pgp mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6.35E+3nMAssay Description:Activity at MDR1 (unknown origin) expressed in MDCK cells assessed as interference with calcein-AM efflux incubated for 30 mins prior to calcein-Am a...More data for this Ligand-Target Pair