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Found 3 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2' and Ligand = 'BDBM50439637'
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human recombinant ACC2 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  10nMAssay Description:Inhibition of human ACC2 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  11nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed