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Found 7 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM10750'
TargetAcetylcholinesterase(Bos taurus (bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  3.03E+4nMAssay Description:Inhibition of bovine AChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  3.18E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of human acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition by Ellma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured every ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  5.24E+4nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  5.24E+4nMAssay Description:Inhibition of AChE in human erythrocytes preincubated for 60 mins followed by substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10750((3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of recombinant human AChEMore data for this Ligand-Target Pair
In DepthDetails PubMed