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Found 4 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM10959'
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10959((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10959((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human erythrocyte AChE using acetyl-(beta-methyl)thiocholine as substrate by enzymatic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10959((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM10959((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed