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Found 7 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM25524'
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataKi:  320nMAssay Description:Competitive inhibition of human AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataKi:  480nMAssay Description:Competitive inhibition of electric eel AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataKi:  920nMAssay Description:Uncompetitive inhibition of electric eel AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataKi:  1.12E+3nMAssay Description:Uncompetitive inhibition of human AChE using acetyl thiocholine iodide as substrate by Lineweaver-Burk double-reciprocal analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of AChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed