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Found 4 Enz. Inhib. hit(s) with Target = 'Acetylcholinesterase' and Ligand = 'BDBM50252257'
TargetAcetylcholinesterase(Anopheles gambiae)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50:  120nMAssay Description:Inhibition of AChE1 in Anopheles gambiae head extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Anopheles gambiae)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50:  190nMAssay Description:Inhibition of AChE1 in Anopheles gambiae head extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Anopheles gambiae)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50:  190nMAssay Description:Inhibition of retinoblastoma protein phosphorylation in human MDA-MB-231 cells after 16 hrs by Hoechst 33342 staining based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293F cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed