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Found 2 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM518192'
TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM518192(US11111247, Example 22)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of human recombinant N-terminal GST tagged ALK2 (147 to end residues) expressed in baculovirus infected in Sf9 cells assessed as loss of p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetActivin receptor type-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM518192(US11111247, Example 22)
Affinity DataIC50:  61nMAssay Description:Inhibition of ALK2 in human HeLa cells assessed as reduction in BMP-7 induced SMAD1 phosphorylation incubated for 1 hr followed BMP-7 stimulation for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed