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Found 4 Enz. Inhib. hit(s) with Target = 'Acyl-CoA (8-3)-desaturase' and Ligand = 'BDBM50535222'
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of D5D in human HepG2 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of D5D in rat RLN10 cells using [14C]DGLA as substrate preincubated for 30 mins followed by substrate addition measured after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataIC50:  19nMAssay Description:Inhibition of D5D in Sprague-Dawley rat liver microsomes using [14C]DGLA as substrate preincubated for 5 mins measured after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50535222(CHEMBL4439992)
Affinity DataKd:  2.70nMAssay Description:Binding affinity to D5D in Sprague-Dawley rat liver microsomes after 150 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed