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Found 3 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM474238'
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474238(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (3-...)
Affinity DataIC50:  1.40nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474238(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (3-...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474238(5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (3-...)
Affinity DataIC50:  13nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent