Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50004587'
TargetAdenosine receptor A1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004587(CHEMBL418101 | 8-Adamantan-1-yl-1,3-dipropyl-3,7-d...)
Affinity DataKi:  1.5nMAssay Description:Tested for binding affinity against Adenosine A1 receptor from rat forebrain membranes, using N6-[3H]- cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004587(CHEMBL418101 | 8-Adamantan-1-yl-1,3-dipropyl-3,7-d...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004587(CHEMBL418101 | 8-Adamantan-1-yl-1,3-dipropyl-3,7-d...)
Affinity DataKi:  13nMAssay Description:Binding affinity against adenosine A1 receptor in guinea pig forebrain membranes using N6-[3H]cyclohexyladenosine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50004587(CHEMBL418101 | 8-Adamantan-1-yl-1,3-dipropyl-3,7-d...)
Affinity DataKi:  13nMAssay Description:Binding affinity against Adenosine A1 receptor from guinea pig forebrain membranes by N6-[3H]- cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50004587(CHEMBL418101 | 8-Adamantan-1-yl-1,3-dipropyl-3,7-d...)
Affinity DataKi:  82nMAssay Description:Antagonist activity against adenosine A1 receptor in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed