Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50163015'
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  6.80nMAssay Description:Inhibition of binding of [3H]N6-cyclohexyladenosine to adenosine A1 receptor of rat whole brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity towards adenosine A1 receptor on rat whole brain membrane using [3H]N6-cyclohexyladenosineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity for Adenosine A1 receptor using [3H]- CHA or [3H]- PIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity at adenosine A1 receptor from rat brain membranes by [3H]N6-cyclohexyladenosine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Warner-Lambert

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]CCPA from rat adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]R-PIA from recombinant human A1AR measured after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  50nMAssay Description:Inhibition of [3H]R-PIA binding to human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163015BDBM50163015((2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed