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Found 8 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50379107'
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]R-PIA from rat forebrain adenosine receptor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Mus musculus)
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  47.9nMAssay Description:Displacement of [3H]R-PIA from human A1 adenosine receptor expressed in CHO cells after 60 min by Perkin Elmer Liquid Scintillation AnalyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  47.9nMAssay Description:Displacement of [3H]R-PIA from human recombinant adenosine receptor-1 expressed in CHO cell membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]N6-phenylisopropyladenosine from recombinant human A1AR expressed in CHO cell membranes after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataEC50:  40.7nMAssay Description:Agonist activity at human recombinant adenosine receptor-1 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production prei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50379107(CHEMBL2012686)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at rat A1A adenosine receptor expressed in CHO-K1 cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed