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Found 4 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a/A2b' and Ligand = 'BDBM50008416'
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50008416(8-Cyclohexyl-1,3,7-trimethyl-3,7-dihydro-purine-2,...)
Affinity DataKi:  0.190nMAssay Description:Binding affinity for adenosine A2 receptor using [3H]- NECA antagonism of adenylate cyclase activation in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50008416(8-Cyclohexyl-1,3,7-trimethyl-3,7-dihydro-purine-2,...)
Affinity DataKi:  190nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50008416(8-Cyclohexyl-1,3,7-trimethyl-3,7-dihydro-purine-2,...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
National Institutes Of Health

Curated by ChEMBL
LigandPNGBDBM50008416(8-Cyclohexyl-1,3,7-trimethyl-3,7-dihydro-purine-2,...)
Affinity DataKi:  1.71E+4nMAssay Description:Binding affinity against adenosine A2 receptor in rat brain using [3H]- CGS 21680 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed