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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM21174'
TargetAdenosine receptor A2a(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21174BDBM21174(N-[2-(furan-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]ZM-241385 from human recombinant adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21174BDBM21174(N-[2-(furan-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-...)
Affinity DataKi:  0.900nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21174BDBM21174(N-[2-(furan-2-yl)-6-(1,3-thiazol-2-yl)pyrimidin-4-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]ZM241385 from rat recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed