BindingDB PrimarySearch

Found 92 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM21220'

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 1nMAssay Description:In vitro inhibition of human neutrophil activation via Adenosine A2A receptor.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 1.5nMAssay Description:Binding affinity against Q89D human adenosine A2A receptor expressed in CHO cells using [3H]- ZM-241385 More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 1.5nM ΔG°: -50.4kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 2.20nMAssay Description:Displacement of [3H]CGS-21680 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 2.20nMAssay Description:Binding affinity of ligand at human adenosine receptors expressed in CHO cell. More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 2.20nMAssay Description:Binding affinity to human A2A adenosine receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 2.20nMAssay Description:Binding affinity to A2A adenosine receptorMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 4.13nMAssay Description:Binding affinity for Adenosine A2A receptor in rat brain membranes using [3H]CGS-21680 More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 5.20nMAssay Description:Binding affinity for HA-tagged mutant human Adenosine A2A receptor (H250N) using [3H]-CGS-21,680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 7.80nMAssay Description:Binding affinity against adenosine A2a receptor from rat striatum using [3H]-CGS- 21680 as a radioligand.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 7.80nMAssay Description:Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatumMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 7.80nMAssay Description:Displacement of [3H]-CGS- 51680 from Adenosine A2A receptor of rat striatum.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 8.40nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 9.30nM ΔG°: -45.8kJ/molepH: 7.4 T: 2°CAssay Description:Binding affinity of ligand at WT and mutant human A2A ARs expressed in COS7 cell. More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 9.70nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10nMAssay Description:Binding affinity against adenosine A2A receptor in rat striatal membranes using [3H]-CGS- 21680.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10nMAssay Description:Inhibition of [3H]- CGS 21680 binding to Adenosine A2A receptor of rat brain membranesMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10nMAssay Description:Displacement of [3 H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from rat adenosine receptor A2A after 60 mins by liquid s...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 10.3nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12nMMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5-N-ethylcarboxamidoadenosine from rat A2A adenosine receptor expressed in HEK293 cell mem...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12nMAssay Description:Displacement of 3[H]CGS21680 from rat A2A adenosine receptor expressed in HEK293 cells after 60 min by Liquid scintillation analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12.2nMAssay Description:Displacement of [3H]CGS-21680 binding to Adenosine A2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12.4nMAssay Description:Binding affinity towards adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12.4nMAssay Description:Displacement of [3H]CGS-21680 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 12.5nMAssay Description:Displacement of [3H]CGS-21680 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 15nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatal membrane after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 15nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 15nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]-NECA from human A2A receptor stably expressed in CHO cell membranes by radioligand competitive binding assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:The membranes prepared from CHO cells transfected with human adenosine A2A receptors were used in binding assays. Nonspecific binding was determined ...More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranesMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Ability to displace radioligand [3H]- CGS 21680 from adenosine A2A receptor on rat striatal membraneMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Rattus norvegicus (rat))
Hokkaido University

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Binding affinity at Adenosine A2A receptor in rat striatal membrane by [3H]ZM-241385 displacement.More data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2a receptor of bovine striatal membraneMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]CGS-21680 binding to adenosine A2A receptors of bovine striatal membranesMore data for this Ligand-Target Pair

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]NECA from human A2A adenosine receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 16nMAssay Description:Displacement of [3H]NECA from human adenosine receptor A2A expressed in CHO cell membranes after 3 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 19.1nMAssay Description:Binding affinity against H278D human adenosine A2A receptor stably transfected in CHO cells using [3H]- ZM-241385 as radioligand.More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 20nMAssay Description:Agonist activity at human adenosine receptor A2AMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 20nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 20nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 20nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Adenosine receptor A2a(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL

BDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)

Ki: 20nMAssay Description:Displacement of [3H]CGS21680 from human A2a adenosine receptor expressed in HEK293 cells after 60 min by Perkin Elmer Liquid Scintillation AnalyzerMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Displayed 1 to 50 (of 92 total ) | Next | Last >>

Filter my 92 hits

Targets 1▿
- Adenosine receptor A2a 92
Publications 50▿
- J Med Chem 46: 4847-59 (2003) 5
- Chem Biol 12: 237-47 (2005) 5
- ACS Med Chem Lett 2: 890-895 (2011) 3
- J Med Chem 62: 1502-1522 (2019) 3
- Bioorg Med Chem 21: 436-47 (2012) 3
- J Med Chem 40: 2588-95 (1997) 3
- J Med Chem 47: 4041-53 (2004) 3
- J Med Chem 55: 4297-308 (2012) 2
- J Med Chem 38: 3581-5 (1995) 2
- J Med Chem 38: 1462-72 (1995) 2
- J Med Chem 58: 3253-67 (2015) 2
- Bioorg Med Chem Lett 20: 1219-24 (2010) 2
- J Med Chem 45: 420-9 (2002) 2
- J Med Chem 50: 1810-27 (2007) 2
- J Med Chem 39: 4211-7 (1996) 2
- Eur J Med Chem 46: 3590-607 (2011) 2
- Bioorg Med Chem Lett 10: 403-6 (2000) 1
- Eur J Med Chem 201: (2020) 1
- J Med Chem 41: 3174-85 (1998) 1
- Biochem Pharmacol 43: 1089-93 (1992) 1
- J Med Chem 38: 1174-88 (1995) 1
- J Med Chem 59: 11006-11026 (2016) 1
- J Med Chem 53: 3954-63 (2010) 1
- Bioorg Med Chem Lett 16: 2416-8 (2006) 1
- Bioorg Med Chem 24: 1793-810 (2016) 1
- J Med Chem 61: 2087-2103 (2018) 1
- J Med Chem 50: 65-73 (2007) 1
- J Med Chem 50: 374-80 (2007) 1
- Naunyn Schmiedebergs Arch Pharmacol 360: 103-8 (1999) 1
- Mol Pharmacol 29: 331-46 (1986) 1
- J Med Chem 41: 1708-15 (1998) 1
- Bioorg Med Chem 18: 7675-99 (2010) 1
- Bioorg Med Chem 25: 471-482 (2017) 1
- Eur J Med Chem 69: 331-7 (2013) 1
- J Med Chem 44: 208-14 (2001) 1
- J Med Chem 55: 538-52 (2012) 1
- J Med Chem 65: 9076-9095 (2022) 1
- J Med Chem 48: 1550-62 (2005) 1
- J Med Chem 35: 2881-90 (1992) 1
- J Med Chem 47: 5535-40 (2004) 1
- J Med Chem 55: 1490-9 (2012) 1
- Bioorg Med Chem Lett 17: 6779-84 (2007) 1
- J Med Chem 51: 1764-70 (2008) 1
- J Med Chem 55: 8075-90 (2012) 1
- J Med Chem 50: 5676-84 (2007) 1
- Eur J Med Chem 179: 310-324 (2019) 1
- J Med Chem 47: 3707-9 (2004) 1
- ACS Med Chem Lett 8: 660-665 (2017) 1
- J Med Chem 59: 947-64 (2016) 1
- J Med Chem 59: 11182-11194 (2016) 1
- ...
Institutions 27▿
- Universit£ 18
- Niddk 8
- National Institute Of Diabetes And Digestive And Kidney Diseases 7
- National Institutes Of Health 5
- Jagiellonian University Medical College 4
- TBA 3
- Monash University 3
- Iiqab (Csic) 3
- Medical College Of Wisconsin 3
- University Of Bonn 3
- Hokkaido University 2
- Novartis Institutes For Biomedical Research 2
- Leiden/Amsterdam Center For Drug Research 2
- Warner-Lambert/Parke-Davis Pharmaceutical Research 1
- Pfizer 1
- National Institutes Of Diabetes And Digestive And Kidney Diseases 1
- National Engineering Research Center For The Emergency Drug 1
- Universitat Wurzburg 1
- Glaxowellcome Medicines Research Centre 1
- Kissei Pharmaceutical 1
- University Of Warwick 1
- National Institute Of Diabetes 1
- Monash University (Parkville Campus) 1
- University Of California San Francisco 1
- University Of Virginia 1
- University Of Leiden 1
- Universita Di Napoli 1
- ...
Affinity: 1 to 1.0E+4 nM▿
- Ki 70
- IC50 6
- EC50 16
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1