Report error Found 47 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM35804'
Affinity DataEC50: 1.40nMAssay Description:Partial agonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as intrinsic activity by measuring cell index change withi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 115nMAssay Description:Functional activity against adenosine A2a receptor from rat aorta.More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human Adenosine A2A receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...More data for this Ligand-Target Pair
Affinity DataKd: 632nMpH: 8.4Assay Description:Saturation binding of wild type human Adenosine A2A receptor at pH 8.4More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as stimulation of [3H]cAMP levels by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKd: 4.40nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at human adenosine A2a receptor expressed in CHO cells assessed as stimulation of cAMP formation after 24 hrsMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at WT receptor in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 22nMpH: 5.5Assay Description:Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 5.5More data for this Ligand-Target Pair
Affinity DataKd: 36nMpH: 6.8Assay Description:Saturation binding of wild type human Adenosine A2A receptor at pH 6.8More data for this Ligand-Target Pair
Affinity DataKd: 99nMpH: 8.4Assay Description:Saturation binding of human Adenosine A2A receptor H250N at pH 8.4More data for this Ligand-Target Pair
Affinity DataKd: 12nMpH: 7.5Assay Description:Saturation binding of human Adenosine A2A receptor H250N at pH 7.5More data for this Ligand-Target Pair
Affinity DataKd: 4.30nMpH: 5.5Assay Description:Saturation binding of mutant human Adenosine A2A receptor (H250N) at pH 5.5More data for this Ligand-Target Pair
Affinity DataKd: 74nMpH: 7.5Assay Description:Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 7.5More data for this Ligand-Target Pair
Affinity DataKd: 7.60nMpH: 6.8Assay Description:Saturation binding of human Adenosine A2A receptor (H250N) at pH 6.8More data for this Ligand-Target Pair
Affinity DataKd: 27nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at V84L mutant receptor in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 7.60nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at H250N mutant receptor in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 115nMAssay Description:Functional activity at Adenosine A2A receptor as vasorelaxation of rat aortaMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Agonist activity at adenosine A2A receptor in human neutrophils assessed as inhibition of fMLP-induced reactive oxygen species release by chemilumine...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against adenosine A1 receptor from rat brain membranes using [3H]cyclohexyladenosine as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2A receptor of rat striatal tissueMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity against adenosine A2a receptor from rat striatum using [3H]-CGS- 21680 as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cell membranes incubated for 120 mins by scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Ability to displace radioligand [3H]- CGS 21680 from adenosine A2A receptor on rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Tested for the binding affinity of A2a receptor by displacing the [3H]-CGS- 21680 in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]NECA from Adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatal membrane after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to rat recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity towards adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in Sf21 cells co-expressing GalphaS2, beta4, gamma2More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Agonist activity at human adenosine receptor A2AMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine 2A receptor after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity for human adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [3H]CGS21680 from A2A adenosine receptor expressed in rat striatal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to human recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
Affinity DataKi: 46.2nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
Affinity DataKi: 46.2nMAssay Description:Displacement of [3H]CGS21680 from human recombinant adenosine A2A receptor expressed in HEK293T cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of [3H]ZM-241385 binding to human adenosine A2A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamido-adenosine from human A2A adenosine receptor expressed in HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarboxamidoadenosine from human adenosine A2a receptor expressed in HEK293 cell...More data for this Ligand-Target Pair
Affinity DataKi: 503nMAssay Description:Displacement of [3H]-ZM24135 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
